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- Doctor Unite 9/27/201998 0 1 20Uncontrolled Diabetes A 51-year-old male patient with type 2 diabetes (T2DM) takes metformin 1000 mg twice daily, glipizide 10mg twice daily, and NPH insulin (35 units in the morning and 10 units in the evening). Despite all the meds, the patient still has frequent hyperglycemic reactions.Show More
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- Cardiologist Connect 10/1/201912 1 1 1Differentially Expressed Proteins in Primary Endothelial Cells Derived From Patients With Acute Myocardial Infarction Endothelial dysfunction is one of the primary factors in the onset and progression of atherothrombosis resulting in acute myocardial infarction (AMI). However, the pathological and cellular mechanisms of endothelial dysfunction in AMI have not been systematically studied.Show More
- Neurologist Connect 10/1/20195 0 0 0Intravenous Glibenclamide Reduces Lesional Water Uptake in Large Hemispheric Infarction Prior studies have shown a linear relationship between computed tomography (CT)-derived radiodensity and water uptake, or brain edema, within stroke lesions. To test the hypothesis that intravenous glibenclamide (glyburide; BIIB093) reduces ischemic brain water uptake, we quantified the lesional net water uptake (NWU) on serial CT scans from patients enrolled in the phase 2 GAMES-RP Trial (Glyburide Advantage in Malignant Edema and Stroke).Show More
- Pharmacist Society 10/1/20198 1 0 1Association of Biologic Therapy With Coronary Inflammation in Patients With Psoriasis as Assessed by Perivascular Fat Attenuation Index Psoriasis is a chronic inflammatory skin disease associated with increased coronary plaque burden and cardiovascular events. Biologic therapy for psoriasis has been found to be favorably associated with luminal coronary plaque, but it is unclear whether these associations are attributable to direct anti-inflammatory effects on the coronary arteries.Show More